Genetic & Genomic Consultation
Dr. Mohammed, Tailor Medical's Chief Science Officer, an internationally recognized genomics expert, will provide a 30-minute educational consultation regarding the most current and relevant genomic testing in the context of your family history, and health status. This educational session will address growing trends in personalized medicine and testing, highlighting tests of particular clinical relevance. In consultation with your Physician, if you choose to have a specific test (or tests) performed, a comprehensive interpretation of the results and further recommendations in relation to disease risk reduction, lifestyle modifications, diagnostic testing and therapeutics, will be provided.
Telomeres are segments of non-functioning DNA that cap the ends of chromosomes, and ensure fidelity of cell replication. The length of telomeres determines the cell age and in turn one's overall biological age. Shorter than average telomeres are associated with metabolic syndrome (obesity, diabetes, high blood pressure, abnormal cholesterol) and excess stress. Interventions that reverse these problems will lengthen telomeres. Repeating telomere length year-over-year permits an estimate of one's rate of aging.
10 SNPs that are related to cholesterol regulation, hypertension, coagulation and other factors that may lead to atherosclerosis and heart attack, are assessed.
4 SNPs related to oxidative protection, detoxification and methylation that are associated with Central Nervous System integrity and neurodegenerative disease, are assessed.
15 SNPs associated with increased risk of impaired detoxification capacity when exposed to environmental toxins, as well as one's susceptibility to adverse drug reactions, are assessed.
ApoE-Cardiovascular & Alzheimer's Risk Assessment
Apolipoprotein E (ApoE) is an essential protein for the metabolism of cholesterol and triglycerides. There are three common genetic variants of the ApoE gene, leading to different performance characteristics of the protein, which in turn is correlated with certain disease susceptibilities. Testing for the genetic variants of the ApoE gene is indicated in those with personal or strong family histories of Alzheimer's disease, heart disease and stroke. Lifestyle modifications and personalized programs are offered to those with ApoE genotypes associated with increased disease risk.
CNV (Copy Number Variation)
CNVs are structural variations in the DNA sequence of cells that result in an abnormal number of copies of one or more segments of the DNA. This leads to a DNA or genomic "fingerprint" that is highly unique to an individual. The catalogue of CNVs in an individual is rapidly becoming an indispensible tool to clarify a host of healthcare issues, including potential susceptibility or resistance to diseases. Having a "baseline" catalogue of one's unique CNV profile when healthy can be important to facilitate the interpretation of genomic data in future illnesses.